Hey Dan,
2-strokes are really a different kind of animal.
With the 4-stroke bergs - It kind of depends on the original muffler, but even the oem enduro muffler is good for 56 horsepower, the straight through mx one on a back to back comparison only gives and extra 1-2 horsepower. That's why on a 400, it isn't necessarily the solution. I've had really large bore silencers on the oem exhaust system without any gain whatsoever and this shows the benefits are to be had in the header and collector area. Once you get the exhaust system working properly, then you can work on the muffler, if you know what I mean. As a general rule of thumb a header pipe of approximately the same diameter as the exhaust valve will work well as will adding just a bit of length to it. Large bore headers on 4 strokes tends to lose torque with gain at the top end. If I remember correctly the 400 has tiny dia. headers to begin with so there is room for expansion, shall we say.
The other thing is that if you have the older style exhaust system with the long silencer and carbon end cap and yellowish pipes rather than chromed the collector didn't work very well.
Hope this helps,
Simon