the first thing you ought to be saying is "ok lads, what is it about race gas/avgas that i don't know?" and not say just like 'YZ' did that "i know, i'll shove race gas in, i know what will happen!'.
that isn't the attitude at all and it's why people write books and make a living out of tuning.
i used to read up on this stuff years ago but i'm rusty now but i think it goes along these lines;
it runs cooler which may not help the metallurgical properties of the valves
the flame is retarded by the fuel; slowed down which may cause an inbalance in the pressure on the top of the piston
the plug won't like it and may be throwing out the wrong kind of spark
it will have the wrong plug heatrange in. these two cause the biggest troubles
you need a quality plug of the correct heat range
a delayed flame will burn all over the bore walls with the piston halfway down the bore as well as all around the exhaust valve. now the temperature of the flame is around 400 degrees as i recall but if the flame is doing a 360 around the exhaust valve, and it's running lean; the temperature will reach 1300 degrees around the exhaust valve.
you can get 13.5 to 1 compression by simply closing up the squish to the correct gap of 1mm or .040" in old money. this way you have a flat piston that takes the pressure down the middle instead of the pressure sliding off a 'crown' - bit like one of tyson's punches! you know-missing!
then you've got the fact that ever since i've been a member here nobody has taken a blind bit of notice when i say to them that to get a correct plug colour you have to SPLIT THE PIPE AND LOOK DOWN THE MIDDLE!
then, if you don't have a proper squish you get pressure down the bore sides which pushes the rings off the bore wall and makes the piston float.
if the piston floats-it slaps! if it slaps the gudgeon pin may take too much pressure. don't forget that yamaha have a history of making the "wrist pin" (USA) too small. i had two SR500's in the seventies and the first WR400's from '98 had them ALL fail!
i haven't even mentioned the jetting yet!
i haven't even mentioned the ignition advance curve yet!
so lads, any more questions?
Taffy